The Virgin of Guadalupe refers to when the Virgin Mary— the mother of Jesus and a very important saint in the Roman Catholic religious tradition—appeared to a man named Juan Diego in Mexico in 1531. She holds a special place in the culture and religious life of many Mexicans and Mexican Americans.   Guadalupe is patroness of the Americas, unborn children, and the New Evangelization.   Our Lady of Guadalupe is the only apparition that left an image of Madonna and Child where Our Lady appears pregnant instead of holding Infant Baby Jesus.